Improving Genome Rearrangement Phylogeny Using Sequen e-Style Parsimony
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منابع مشابه
Inferring Genome Rearrangement Phylogeny based on Maximum Likelihood of Gene Adjacencies
Background: Recent technological advances in sequencing and computation have now made it possible to obtain gene content and gene orders within genomes on the order of 10 base pairs in size or more. These orders can be changed by rearrangement events such as inversions and duplications. Since these events are rare, they enable phylogenetic reconstructions to extend far back in time. Many softwa...
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Genome rearrangement analysis has attracted a lot of attentions in phylogenetic computation and comparative genomics. Solving the median problems based on various distance definitions has been a focus as it provides the building blocks for maximum parsimony analysis of phylogeny and ancestral genomes. The Median Problem (MP) has been proved to be NP-hard and although there are several exact or ...
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Genome rearrangements are a valuable source of information about early evolution, as well as an important factor in speciation processes. Reconstruction of ancestral gene orders on a phylogeny is thus one of the crucial tools contributing to understanding of evolution of genome organization. For most models of evolution, this problem is NP-hard. We have developed a universal method for reconstr...
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تاریخ انتشار 2008